Construction of 7-Diethylaminocoumarins Promoted by an Electron-Withdrawing Group

نویسندگان

چکیده

The coumarin skeleton has been a focus of attention for many years, and its fluorescence properties vary depending on the substituents. Fluorescent derivatives are useful tools strategies have developed their synthesis. Although 7-diethylaminocoumarin excellent properties, it is unstable. We facile strategy synthesis by increasing electrophilicity ynone moiety to promote nucleophilic addition reactions cyclization. reaction tolerates variety substitutions at 4-position.

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ژورنال

عنوان ژورنال: Chemical & Pharmaceutical Bulletin

سال: 2021

ISSN: ['0009-2363', '1347-5223']

DOI: https://doi.org/10.1248/cpb.c21-00228